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Clive Roper
BSc, PhD, CBiol, CSci, ERT, FRSB

Director, Roper Toxicology Consulting Limited

About: About

Experience

Director, Owner and Founder, Roper Toxicology Consulting Limited

March 2021 - Present

January 2021 - Present

August 2010 - February 2020

UK NC3Rs

Charles River Laboratories, Edinburgh, UK

  • People management

  • Multimillion dollar budget

  • Business and department growth

  • BD

  • NAMs development

  • In vitro skin absorption

  • In vitro respiratory toxicology

  • In vitro safety pharmacology

  • Genetic toxicology

  • In vitro metabolism

  • Speaker

  • Leader

  • 3Rs working group (corporate)

  • Technology evaluation (corporate)

March 2020 - February 2021

Charles River Laboratories, Edinburgh, UK

  • People management

  • Multimillion dollar budget

  • Business and department growth

  • BD

  • NAMs development

  • In vitro skin absorption

  • In vitro respiratory toxicology

  • In vitro safety pharmacology

  • Advanced in vitro tissue models

  • Speaker

  • Leader

  • 3Rs working group (corporate)

  • Technology evaluation (corporate)

June 1996 - August 2010

Charles River Laboratories Edinburgh Limited

  • Scientific Manager (January 2003 - August 2010)

  • Study Director (July 1997 - December 2002)

  • Research Officer (June 1996 - June 1997).

  • Founding member and board member of the 3Rs Collaborative

  • Vice President and board member of ESTIV

  • Board chairperson of PeptiMatrix

  • Member of the UK NC3Rs board

  • European Registered Toxicologist (ERT)

  • Fellow of the Royal Society of Biology (FRSB)

  • Active member of leading societies like ASCCT, SOT, ACT, and ACTC

About: CV

Professional Leadership

  • Founding member and board member of the 3Rs Collaborative

  • Vice President and board member of ESTIV

  • Board chairperson of PeptiMatrix

  • Member of the UK NC3Rs board

  • European Registered Toxicologist (ERT)

  • Fellow of the Royal Society of Biology (FRSB)

  • Active member of leading societies like ASCCT, SOT, ACT, and ACTC

Education 

October 1990 - April 1994

DOCTOR OF PHILOSOPHY

Department of Environmental and Occupational Medicine, Newcastle University & Unilever Research, Sharnbrook, Bedfordshire, UK.

  • In vitro skin absorption and toxicology

  • PhD thesis: In vitro approaches to the prediction of percutaneous absorption and metabolism: a study of ethoxylates.

September 1987 - June 1990

BACHELOR OF SCIENCE 

Department of Agricultural Biochemistry and Nutrition, Newcastle University.

  • Agricultural Biochemistry and Nutrition, BSc (Hons) 2:1.

About: CV

Achievements 

Developing a NAM for respiratory toxicology, representing this to the US EPA Special Advisory Panel, receiving a personal invitation to attend the EPA NAM conferences, being acknowledged as an EPA stakeholder for their animal-free 2035 plans and writing the NAM as a case study now accepted for publication by the OECD
• 4 of my peer review papers are quoted in OECD test guidelines (OECD 428 and OECD 492)

Current Memberships

  • Board member at the 3Rs Collaborative (3RsC) 

  • Board member at the Nationale Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs)

  • Board member at the European Society of In Vitro Toxicology (ESTIV)

  • Fellow of the Royal Society of Biology (FRSB)

  • Chartered Biologist (CBiol)

  • Chartered Scientist (CSci)

  • Member of the European Registered Toxicologist (ERT)​

  • Member of the Society of Toxicology (SOT)​

  • Member of the Regulatory and MPS Subgroups of the 3RsC ​

  • Member of the American Society for Cellular and Computational Toxicology (ASCCT)

  • Member of the International Microphysiological Systems Society (IMPSS)

  • Member of The Roundtable of Toxicology Consultants (toxconsultants.com)

  • Member of the RESPTox Acute In Vitro Respiratory Group

About: Text

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