
Clive Roper
BSc, PhD, CBiol, CSci, ERT, FRSB
Director, Roper Toxicology Consulting Limited
Experience
April 2021Â - Present
Director, Owner and Founder, Roper Toxicology Consulting Limited
March 2021Â - Present
January 2021Â - Present
August 2010 - February 2020
UK NC3Rs
Charles River Laboratories, Edinburgh, UK
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People management
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Multimillion dollar budget
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Business and department growth
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BD
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NAMs development
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In vitro skin absorption
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In vitro respiratory toxicology
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In vitro safety pharmacology
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Genetic toxicology
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In vitro metabolism
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Speaker
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Leader
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3Rs working group (corporate)
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Technology evaluation (corporate)
March 2020Â - February 2021
Charles River Laboratories, Edinburgh, UK
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People management
-
Multimillion dollar budget
-
Business and department growth
-
BD
-
NAMs development
-
In vitro skin absorption
-
In vitro respiratory toxicology
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In vitro safety pharmacology
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Advanced in vitro tissue models
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Speaker
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Leader
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3Rs working group (corporate)
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Technology evaluation (corporate)
June 1996 - August 2010
Charles River Laboratories Edinburgh Limited
Scientific Manager (January 2003 - August 2010)
Study Director (July 1997 - December 2002)
Research Officer (June 1996 - June 1997).
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Founding member and board member of the 3Rs Collaborative
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Vice President and board member of ESTIV
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Board chairperson of PeptiMatrix
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Member of the UK NC3Rs board
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European Registered Toxicologist (ERT)
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Fellow of the Royal Society of Biology (FRSB)
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Active member of leading societies like ASCCT, SOT, ACT, and ACTC
Professional Leadership
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Founding member and board member of the 3Rs Collaborative
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Vice President and board member of ESTIV
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Board chairperson of PeptiMatrix
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Member of the UK NC3Rs board
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European Registered Toxicologist (ERT)
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Fellow of the Royal Society of Biology (FRSB)
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Active member of leading societies like ASCCT, SOT, ACT, and ACTC
Education
October 1990Â - April 1994
DOCTOR OF PHILOSOPHY
Department of Environmental and Occupational Medicine, Newcastle University & Unilever Research, Sharnbrook, Bedfordshire, UK.
In vitro skin absorption and toxicology
PhD thesis: In vitro approaches to the prediction of percutaneous absorption and metabolism: a study of ethoxylates.
September 1987Â - June 1990
BACHELOR OF SCIENCE
Department of Agricultural Biochemistry and Nutrition, Newcastle University.
Agricultural Biochemistry and Nutrition, BSc (Hons) 2:1.
Achievements
• Developing a NAM for respiratory toxicology, representing this to the US EPA Special Advisory Panel, receiving a personal invitation to attend the EPA NAM conferences, being acknowledged as an EPA stakeholder for their animal-free 2035 plans and writing the NAM as a case study now accepted for publication by the OECD
• 4 of my peer review papers are quoted in OECD test guidelines (OECD 428 and OECD 492)
Current Memberships
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Board member at the 3Rs Collaborative (3RsC)
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Board member at the Nationale Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs)
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Board member at the European Society of In Vitro Toxicology (ESTIV)
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Fellow of the Royal Society of Biology (FRSB)
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Chartered Biologist (CBiol)
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Chartered Scientist (CSci)
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Member of the European Registered Toxicologist (ERT)​
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Member of the Society of Toxicology (SOT)​
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Member of the Regulatory and MPS Subgroups of the 3RsC ​
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Member of the American Society for Cellular and Computational Toxicology (ASCCT)
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Member of the International Microphysiological Systems Society (IMPSS)
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Member of The Roundtable of Toxicology Consultants (toxconsultants.com)
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Member of the RESPTox Acute In Vitro Respiratory Group